fb_script

Children with type 1 diabetes at risk of acute kidney injury following DKA

A new study has found that children with type 1 diabetes (T1D) who are hospitalised for Diabetic Ketoacidosis (DKA) are more likely to develop acute kidney injury (AKI), a sudden episode of renal failure or damage. DKA is a severe complication that occurs with prolonged hyperglycaemia. It may occur at the initial presentation of newly diagnosed T1D or in someone with pre-existing T1D in times of illness or insulin omission.
Read More

First audit of national data from Australia’s unique registry highlights an urgent need to improve glycaemic control in young people with T1D.

International diabetes registries report that many young people with type 1 diabetes (T1D) do not meet their recommended targets for glycaemic control, however relevant Australian data has been lacking. The Australasian Diabetes Data Network (ADDN) funded by the Type 1 Diabetes Clinical Research Network (T1DCRN) and led by the Australasian Paediatric Endocrine Society (APEG) and Australian Diabetes Society (ADS) is a secure, centralised database that captures de-identified clinical data from thousands of people after diagnosis of T1D on a single purpose built database. The ADDN study group has published the first national surveillance of glycaemic control and management of type 1 diabetes in young people in Australia.

Read More

TEDDY project highlights benefit of being diagnosed before symptoms of type 1 diabetes appear

There are a number of genes linked to type 1 diabetes (T1D), but not everyone with genetic predisposition develops the condition. This suggests that there are likely environmental triggers that stimulate the development of T1D. The Environmental Determinants of Diabetes in the Young (TEDDY), a study part supported by JDRF, is a large prospective, longitudinal cohort study investigating the environmental factors that may contribute to T1D development.

vaccine

An article published by the TEDDY study group in Paediatric Diabetes this month highlights the benefits of early diagnosis of children at risk of T1D. Children involved in TEDDY are from six large clinical centres across the US and Europe and are being followed from birth until 15 years of age to track diet, illness, body growth and other life experiences.

Read More

T1DCRN awards $4.5 million in innovative research grants

The Hon Simon Birmingham, Minister for Education and Training, and The Hon Greg Hunt, Minister for Health and Minister for Sport, have today announced the recipients of Innovation Award grants for research into type 1 diabetes.

Three bold, promising research projects have been selected and will benefit from $4.5 million in funding from the Type 1 Diabetes Clinical Research Network (T1DCRN), itself an innovative clinical research program led by JDRF Australia and funded by a Special Research Initiative through the Australian Research Council (ARC).

imageedit_2_2405540522

In an exciting paradigm shift that aims to accelerate patient impact, the research funded by the Innovation Award grants will explore new directions in the search for a cure for type 1 diabetes, including concepts that have never before been investigated.

Read More

Consensus report to help people with type 1 diabetes exercise safely

A report by leading type 1 diabetes experts from around the world has for the first time provided consensus on managing blood glucose levels safely while exercising.

dumbell

The report, ‘Exercise management in type 1 diabetes: a consensus statement’ was published in the Lancet Diabetes and Endocrinology journal and involved a team of 21 researchers, including T1DCRN researchers Professor Tim Jones, Professor Paul Fournier and Dr Carmel Smart. They undertook a review of current published studies to understand the activity levels of those living with type 1 diabetes and how different types of exercise affect blood glucose levels.  Read More

Australian diabetes expert receives Australia Day honour

JDRF is proud to congratulate Professor Mark Cooper, Head of Diabetes in the Faculty of Medicine, Nursing and Health Sciences at Monash University, who was awarded an AO (Officer in the General Division of the Order of Australia) on Australia Day this month.

imageedit_1_3004952851

This award is the most prestigious means of recognising outstanding members of the community at a national level.

Read More

Evidence building for possible virus link in T1D development

A new study suggests a link between enteroviruses, and the development of type 1 diabetes (T1D). This study, part-funded by JDRF, isn’t the first to find this link but the authors say it’s the largest and most definitive study of its kind to date.

virus-infected-cells-resized

Professor Keikki HyÖty and Dr Hanna Honkanen led this study published in Diabetologia at the University of Tampere in Finland. They found that children at high risk of T1D who then go on to develop the disease, had a higher number of enterovirus infections compared to those without the disease.

Read More

World leading experts discuss innovative ideas in T1D research

In early December, the Type 1 Diabetes Clinical Research Network (T1DCRN) brought together leading national and international experts in type 1 diabetes (T1D) to the Woolcock Institute in Sydney for the 2016 BRIdGE Symposium.

T1DCRN 2016 Symposium
Prof Chantal Mathieu, Director of the Endocrinology Clinic at the University Hospital of Leuven

This year’s theme was innovation in autoimmunity and complications. A mix of high calibre clinicians, clinical researchers and basic researchers from areas such as immunology, genetics and paediatrics mingled and shared their novel ideas for accelerating research in T1D.

Read More

The need to screen for additional autoimmune diseases

People with type 1 diabetes (T1D) often develop other autoimmune diseases, but the frequency and predictive factors for development have not been characterised.

lab research

While the mechanisms for T1D are still under investigation, it is thought there are common immune system pathways that may be similar across more than one, or all autoimmune diseases.  Read More

Carb counting: Could there be a better way?

The current gold standard for calculating mealtime insulin in people with type 1 diabetes is carbohydrate counting using the carbohydrate to insulin ratio – the amount of insulin that will cover a certain amount of carbohydrates. Recent research and clinical observations from continuous glucose monitoring (CGM) data has seen that people can experience delayed high blood glucose levels (hyperglycaemia) hours after eating a meal high in fat and/or protein.  Read More