TrialNet is an international collaborative network that aims to prevent, delay and reverse the progression of type 1 diabetes, involving United States, Canada, Finland, United Kingdom, Italy, Germany, Australia and New Zealand.
TrialNet in Australia/New Zealand is led by A/Prof John Wentworth at Walter & Eliza Hall Institute (WEHI) in collaboration with Prof Peter Colman AM.
Image credit: University of Pennsylvania
Infection with a common virus known as coxsackievirus B has long been thought to be associated with the development of type 1 diabetes. Now, researchers have published evidence that this virus could be driving the activity of the very genes that increase the risk of developing type 1 diabetes. Read More
Giving probiotics to babies in the first few weeks of life may lower their risk of developing type 1 diabetes, a recent study has found.
The study, published in JAMA Pediatrics found that children who were given probiotics within the first 27 days of life had a 60% reduction in the risk of developing islet autoimmunity, compared with children who were first given probiotics after 27 days or not at all. Read More
Our immune systems vary with the seasons, according to a study led by the University of Cambridge that could help explain why conditions such as type 1 diabetes are more frequently diagnosed during the winter months.
The study, funded by JDRF, the Wellcome Trust and the NIHR Cambridge Biomedical Research Centre was published today in the journal Nature Communications. The study shows that the activity of almost a quarter of our genes (5,136 out of 22,822 genes tested) differs according to the time of year, with some more active in winter and others more active in summer. This seasonality also affects our immune cells and the composition of our blood and fat tissue.
Scientists have known for some time that various diseases, including autoimmune diseases such as type 1 diabetes and multiple sclerosis, display seasonal variation. However, this is the first time that researchers have shown that this may be down to seasonal changes in how our immune systems function. Read More