A new study has found that children with type 1 diabetes (T1D) who are hospitalised for Diabetic Ketoacidosis (DKA) are more likely to develop acute kidney injury (AKI), a sudden episode of renal failure or damage. DKA is a severe complication that occurs with prolonged hyperglycaemia. It may occur at the initial presentation of newly diagnosed T1D or in someone with pre-existing T1D in times of illness or insulin omission.
International diabetes registries report that many young people with type 1 diabetes (T1D) do not meet their recommended targets for glycaemic control, however relevant Australian data has been lacking. The Australasian Diabetes Data Network (ADDN) funded by the Type 1 Diabetes Clinical Research Network (T1DCRN) and led by the Australasian Paediatric Endocrine Society (APEG) and Australian Diabetes Society (ADS) is a secure, centralised database that captures de-identified clinical data from thousands of people after diagnosis of T1D on a single purpose built database. The ADDN study group has published the first national surveillance of glycaemic control and management of type 1 diabetes in young people in Australia.
There are a number of genes linked to type 1 diabetes (T1D), but not everyone with genetic predisposition develops the condition. This suggests that there are likely environmental triggers that stimulate the development of T1D. The Environmental Determinants of Diabetes in the Young (TEDDY), a study part supported by JDRF, is a large prospective, longitudinal cohort study investigating the environmental factors that may contribute to T1D development.
An article published by the TEDDY study group in Paediatric Diabetes this month highlights the benefits of early diagnosis of children at risk of T1D. Children involved in TEDDY are from six large clinical centres across the US and Europe and are being followed from birth until 15 years of age to track diet, illness, body growth and other life experiences.
Senator The Hon Simon Birmingham, Minister for Education and Training, and The Hon Greg Hunt MP, Minister for Health and Minister for Sport, have today announced the recipients of Innovation Award grants for research into type 1 diabetes.
Three bold, promising research projects have been selected and will benefit from $4.5 million in funding from the Type 1 Diabetes Clinical Research Network (T1DCRN), itself an innovative clinical research program led by JDRF Australia and funded by a Special Research Initiative through the Australian Research Council (ARC).
In an exciting paradigm shift that aims to accelerate patient impact, the research funded by the Innovation Award grants will explore new directions in the search for a cure for type 1 diabetes, including concepts that have never before been investigated.
A report by leading type 1 diabetes experts from around the world has for the first time provided consensus on managing blood glucose levels safely while exercising.
The report, ‘Exercise management in type 1 diabetes: a consensus statement’ was published in the Lancet Diabetes and Endocrinology journal and involved a team of 21 researchers, including T1DCRN researchers Professor Tim Jones, Professor Paul Fournier and Dr Carmel Smart. They undertook a review of current published studies to understand the activity levels of those living with type 1 diabetes and how different types of exercise affect blood glucose levels. Read More
A new study suggests a link between enteroviruses, and the development of type 1 diabetes (T1D). This study, part-funded by JDRF, isn’t the first to find this link but the authors say it’s the largest and most definitive study of its kind to date.
Professor Keikki HyÖty and Dr Hanna Honkanen led this study published in Diabetologia at the University of Tampere in Finland. They found that children at high risk of T1D who then go on to develop the disease, had a higher number of enterovirus infections compared to those without the disease.
In early December, the Type 1 Diabetes Clinical Research Network (T1DCRN) brought together leading national and international experts in type 1 diabetes (T1D) to the Woolcock Institute in Sydney for the 2016 BRIdGE Symposium.
This year’s theme was innovation in autoimmunity and complications. A mix of high calibre clinicians, clinical researchers and basic researchers from areas such as immunology, genetics and paediatrics mingled and shared their novel ideas for accelerating research in T1D.
People with type 1 diabetes (T1D) often develop other autoimmune diseases, but the frequency and predictive factors for development have not been characterised.
While the mechanisms for T1D are still under investigation, it is thought there are common immune system pathways that may be similar across more than one, or all autoimmune diseases. Read More
The current gold standard for calculating mealtime insulin in people with type 1 diabetes is carbohydrate counting using the carbohydrate to insulin ratio – the amount of insulin that will cover a certain amount of carbohydrates. Recent research and clinical observations from continuous glucose monitoring (CGM) data has seen that people can experience delayed high blood glucose levels (hyperglycaemia) hours after eating a meal high in fat and/or protein. Read More
JDRF-funded researcher Professor Mark Cooper, Chief Scientific Officer and Head of the Diabetes Division at Baker IDI Heart and Diabetes Research Institute, has become the first Australian to receive the prestigious Claude Bernard award from the European Association for the Study of Diabetes this month. Read More